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Pharmaceuticals



Sphere Fluidics to increase supply of biocompatible surfactant for droplet microfluidics


19th February 2020
Sphere Fluidics, a company commercializing single-cell analysis systems based on its patented picodroplet technology, is investing in the production and supply of its proprietary biocompatible surfactant, Pico-Surf, for droplet generation and processing. Pico-Surf is an animal-origin-free biocompatible surfactant optimized to support the formation of aqueous solution-in-oil picodroplets and is designed to work across a broad range of microfluidic systems, including Sphere Fluidics’ proprietary single cell analys platforms and applications, such as molecular biology assays, cell secretion assays and cell growth studies. The company will expand its operations to meet demand for large-scale commercial supply of the surfactant for use in a wide range of microfluidic application workflows.
 
The patented molecular structure of Pico-Surf stabilizes droplets, and retains and protects their cellular and molecular contents over a wide range of temperatures and biological conditions, helping to ensure high cell viability for improved assay performance. Droplets generated using Pico-Surf show low-endpoint interfacial tension and critical micelle concentration in comparison to other commercially available surfactants. The purity and quality of the surfactant also enables a more efficient droplet sorting process at low voltage. The ready-to-use surfactant is available in large batches or made-to-order.